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Chemotherapy may not be needed to treat cancer: Research

A team of 11 scientists from the Cleveland Clinic in the US and a researcher from Allahabad University (AU) have found a way in which chemo and radiation therapy will not be required to kill cancer cells.

The work of the team led by Yang Li, Professor of Cancer Biology at the Cleveland Clinic, and assisted by Munish Pandey, Assistant Professor at the Department of Biochemistry, AU, has been published in the prestigious journal ‘Oncogene by Nature’.

The research bears significance as the work promises a treatment using which the cancer patients will be saved from the side effects of chemo and radiation therapy.

After its successful experiment on rats, efforts are now being intensified to apply it on the human body.

Pandey said: “The study may give relief to cancer patient who undergoes chemotherapy. Chemotherapy uses radiation and other drugs which has many side effects and evoke immune system that causes severe pain and allergic reaction. The team has earlier developed knockout mice for miR-21 and the same was published in ‘Proceedings of the National Academy of Sciences’ of the US (PNAS) journal. MicroRNA-21 (small non-coding RNA) is one of the most abundant microRNAs in mammalian cells that regulates apoptosis (programme cell death) and oncogenic effects.

“I have worked along with the American scientists and invented an alternative to chemotherapy and drugs in the treatment of cancer, which damage normal cells along with cancer cells during cancer treatment. This successful experiment was done by a team of 11 scientists in the Cleveland Clinic and Yang Li. Our team while experimenting on mice injected its anti-sense into mice to make miR-21 ineffective.”

Following this, it was found that the tumour formed in the body of the rat gradually became smaller and some tumours disappeared completely.

This experiment went on for a year in America. However, it has not yet been used on the human body. Now the effort has been intensified to apply it on the human body, Pandey said.

He added that due to cancer, tumours are formed in the body which are eliminated through chemotherapy and drugs. In this process of treatment along with cancer cells, normal cells are also damaged and has a negative effect on the body.

The group is working on other programmed cell death mechanisms, microRNAs and chemeric antigen T-cell therapy to tackle carcinogenicity in mice model.

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Apple iPhone 14 Pro to come with Bigger camera: Report

Apple is expected to announce the iPhone 14 series in or around September and now a new report suggests the Pro models would come with a big camera upgrade.
Current Pro iPhones ship with a 12MP camera onboard. However, iPhone 14 Pro models will feature a 48MP camera.
According to TrendForce, a 48 million pixel primary camera is expected to be introduced to the iPhone 14 Pro series (tentative name) that Apple will release this year, further reducing 12 million pixel products to a 15 per cent share in 2022.
Recently, Apple analyst Ming-Chi Kuo also claimed that the 2022 iPhone 14 Pro and 14 Pro Max would be shifting over to a hole-punch cutout for the camera.
Apple has reportedly advised major US carriers to prepare for the launch of eSIM-only smartphones by September this year.
It is possible that Apple might remove the physical SIM card slot starting with some iPhone 14 models, rather than some iPhone 15 models as originally rumoured.
It is also said that there will be support for two eSIM cards, ensuring dual SIM functionality. The removal of the SIM card slot could further improve water resistance.
The next flagship series, the iPhone 14 line-up, will come with up to 2 TB of storage.
Apple will adopt QLC flash storage for next year’s iPhone, thanks to the newer storage technology, it will increase capacity to 2 TB.

 

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WhatsApp will STOP working on THESE smartphones soon – Check full list

WhatsApp is all set to stop working on various iPhones and Androids in the year 2022. It was recently reported that the Facebook-owned messaging app would not work on the older versions of Android and iOS.

If these reports are true then you will be blocked out of WhatsApp and will not be able to send or receive messages, photos, or videos on your old phones.

Notably, the ones who will be able to use messaging app WhatsApp are those with a smartphone that support Android OS 4.1 and above and iOS 10 and above.

Before WhatsApp in your phone stops working, it is necessary to check whether the version of the software on your phone matches the requirement. Android and iOS users can check the same via accessing the mobile phone settings.

It is important to note that, WhatsApp India is yet to formally announce the same. However, WhatsApp will not support many older phones in Brazil, according to a report in Sproutweird.

Here is a complete list of smartphones that WhatsApp will stop working on in 2022.

Android Phones

Archos 53 Platinum
HTC Desire 500
Samsung galaxy trend lite
Samsung Galaxy Trend II
Mini Samsung Galaxy S3
Caterpillar Cat B15
Sony Xperia M
THL W8
ZTE grand x quad v987
ZTE Grand Memo
Samsung galaxy ace 2
LG Lucid 2
LG Optimus F7
LG Optimus L3 II Dual
LG Optimus F5
LG Optimus L5 II
LG Optimus L5 II Dual
LG Optimus L3 II
LG Optimus L7 II Dual
LG Optimus L7 II
LG Optimus F6
LG Act
LG Optimus L4 II Dual
LG Optimus F3
LG Optimus L4 II
LG Optimus L2 II
LG Optimus F3Q
Vico sync five
Vico darkknight
Samsung Galaxy Xcover 2
Huawei Ascend G740
ZTE Grand S Flex
Lenovo A820
Huawei Ascend Mate
ZTE V956 – UMI X2
Huawei Ascend D2
Samsung galaxy core
Faea F1

iPhones

Apple iPhone SE (16GB)
Apple iPhone SE (32GB)
Apple iPhone 6S (64GB)
Apple iPhone 6S Plus (128 GB)
Apple iPhone 6S Plus (16GB)
Apple iPhone 6S Plus (32GB)
Apple iPhone 6S Plus (64GB)
Apple iPhone SE (64GB)
Apple iPhone 6S (128 GB) A
Apple iphone 6s (16gb)
Apple iPhone 6S (32GB)

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COVID 19

Bars, theatres can open with 50% capacity, why not gym?: Paresh Rawal

After the closure of many things especially gyms due to increasing covid19 cases in Maharashtra, Bollywood actor Paresh Rawal reacted to this and asked that bars, theatres etc are opened with 50% but why not the gyms?

Taking a Twitter Paresh tweeted, “Trains, theatres and bars and restaurants etc. are allowed to remain open with 50% capacity, but gyms are not !!! What is the logic behind this? Is it a crime to take care of your health? Isn’t this an essential service?”

Amid the rapid increase of the covid19 cases in Maharashtra, the state government on Saturday introduced new rules which says theatres, restaurants and bars can be opened with 50 per cent capacity. While swimming pools, gyms, spas, wellness centres will remain closed.

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Covid-19 Stats

29 Jan 2022, 12:33 PM (GMT)

Coronavirus Stats

40,854,851 Total Cases
493,218 Death Cases
38,346,367 Recovered Cases

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